Name : John Totman
Title : Dr.
Current Position :

Head of Imaging Operations

Adjunct Assistant Professor (NUS DDR)

Email address : John_Totman@circ.a-star.edu.sg
Contact Number : 6516 5057
Employment History
May 2012 – to Present. A*STAR-NUS Clinical Imaging Research Centre Singapore.

http://www.circ.nus.edu.sg

Aug 2010 – May 2012 R&D Imaging Support Unit, Nottingham University Hospitals NHS Trust, Nottingham.

http://www.nuh.nhs.uk/mpce/IRDSU.aspx

Feb 2008 – Aug 2010 Division Imaging Science, Kings College London, London.

http://www.kcl.ac.uk/schools/medicine/research/imaging

2005- Feb 2008 Brain and Body Centre, University of Nottingham, Nottingham.

www.brainbody.nottingham.ac.uk ; http://www.magres.nottingham.ac.uk

1998- 2005 General MRI Dept., King’s College Hospital NHS Trust, London.

http://www.kch.nhs.uk/

1997 - 1998 Academic Radiology Dept. Sheffield University. Sheffield.

http://www.shef.ac.uk/radiology/

1995 - 1997   Neuroimaging Dept. Southeast Thames regional neurosciences centre, King’s College Hospital and South London & Maudsley NHS Trusts, London 

http://www.iop.kcl.ac.uk ; http://www.kingsch.nhs.uk./ ; www.slam.nhs.uk/

1994 - 1995 Radiology Dept. The Royal London Hospital NHS Trust, Whitechapel, London.

http://www.bartsandthelondon.org.uk/

Feb 1994 -  May1994 Radiology Dept. Mount Isa Base Hospital, Mount Isa, Queensland, Australia.
Oct 1993 – Jan 1994 X-Ray and Ultrasound. Double Bay, Sydney, Australia.
Jan 1990 - 1993 Radiology Dept. The Homerton Hospital / St Bartholomew’s Hospital. London.
Oct 1989 – Jan 1990 Radiology Dept. The Royal London Hospital. Whitechapel, London.

 

 

Qualifications

2005 - 2011 PhD “Characterisation of PC-MRI Data”. Sir Peter Mansfield Magnetic Resonance Centre, School Physics and Astronomy. University of Nottingham, Nottingham.

2000 - 2003 MSc. Magnetic Resonance Technology. “Pilot study of the efficacy of perfusion MRI as a technique in the detection of changes in the hepatic perfusion index”. The Centre of Magnetic Resonance, University of Queensland, Queensland, Australia.

1986 - 1989 Diploma of the College of Radiography. The London Hospital School of Radiography and Radiotherapy. London.

 

 

Research Interest

Implementation of PET/MRI in a research setting.

 

 

Publications

Review of Clinical Cardiac MRI MD Sosin, HR Khan, JJ Totman, KS Pointon 2013 Imaging, 22

Effects of various food ingredients on gall bladder emptying L Marciani, EF Cox, CL Hoad, JJ Totman C Costigan, G Singh, V Shepherd, L Chalkley, M Robinson, R Ison, PA Gowland, RC Spiller 2013 Eur J Clin Nutr

Preventing Gastric Sieving by Blending a Solid/Water Meal Enhances Satiation in Heathy Humans L Marciani, N Hall, SE Pritchard, EF Cox, JJ Totman, M Lad, CL Hoad, TJ Foster, PA Gowland RC Spiller 2012 American Journal of Clinical Nutrition Jul;142(7):1253-8

Task-related Default Mode Network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate. E Liddle, G Scerif, M Batty, M Groom, JJ Totman, M  Liotti,  C  Hollis, P  Liddle. 2010 Journal of Child Psychology and Psychiatry. 52;7 761-771

Sequence optimization to reduce velocity offsets in cardiovascular magnetic resonance volume flow quantification - A multi-vendor study MP Rolf, MB Hofman, PD Gatehouse, KM Bloch, MW Heymmans, T Ebbers, MJ Graves, JJ Totman, B Werner, A van Rossum, PJ Kilner RM Heethaar. 2011 J Cardiovasc Magn Reson. 13:18

Realtime fusion of cardiac magnetic resonance imaging and computed tomography venography with X-ray fluoroscopy to aid cardiac resynchronisation therapy implantation in patients with persistent left superior vena cava. SG Duckett, M Ginks, AK Shetty, BR Knowles, JJ Totman, A Chiribiri, YL Ma, R Razavi, T Schaeffter, G Carr-White, K Rhode, CA Rinaldi. Europace. 2011 Feb;13(2):285-6. Epub 2010 Oct 25.

Simultaneous PET-MR acquisitions and MR-derived motion fields for correction of non-rigid motion in PET. C Tsoumpas, JE Mackewn, P Halsted, AP King, C Buerger, JJ Totman, T Schaeffter, PK Marsden. 2010 Annals of Nuclear Medicine. 24 (10) 745-750

Effects of a 5-HT3 antagonist on fasting and postprandial small bowel water content assessed by magnetic resonance imaging L Marciani,EF Cox, CL Hoad, S Pritchard, JJ Totman, S Foley, A Mistery, S Evans, PA Gowland and RC Spiller. : Alimentary Pharmacology & Therapeutics 2010 32:5; 65-663 2010

Performance evaluation of an MRI-compatible pre-clinical PET system using long optical fibres. JE Mackewn, D Strul, G Charles-Edwards, SF Keevil, T Schaeffter, WA Hallett, P Halsted, RA Page, JJ Totman, P Liepins, SCR Williams, PK Marsden. IEEE Transactions On Nuclear Science 2010 57:3;  1052-1062 2010

Postprandial changes in small bowel water content in healthy subjects and patients with irritable bowel syndrome. L Marciani,EF Cox, CL Hoad, S Pritchard, JJ Totman, S Foley, A Mistery, S Evans, PA Gowland and RC Spiller. Gastroenterology. 2010;138:469-477.

Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurements. PD Gatehouse, MP Rolf, MJ Graves, MB Hofman, JJ Totman, B Werner, RA Quest, Y Liu, J von Spiczak, M Dieringer, DN Firmin, A van Rossum, M Lombardi, J Schwitter, J Schulz-Menger, PJ Kilner. J Cardiovasc Magn Reson. 2010 Jan 14;12:5.

Acceleration of whole heart and targeted coronary artery imaging at 3 T with a 32-channel coil A Wiethoff, JJ Totman, M Makowski, S Arancibia, T Schaeffter, R Botnar J Cardiovasc Magn Reson. 2010 Vol: 12 Issue: Suppl 1 P54

Gastric emptying of three liquid oral preoperative metabolic preconditioning regimens measured by magnetic resonance imaging in healthy adult volunteers: a randomised double-blind, crossover study. DN Lobo, PO Hendry, G Rodrigues, L Marciani, JJ Totman, JW Wright, T Preston, P Gowland, RC Spiller, KCH Fearon. Clin Nutr. 2009 Dec;28(6):636-41.

Characterization of the time course of the superior mesenteric, abdominal aorta, internal carotid and vertebral arteries blood flow response to the oral glucose challenge test using magnetic resonance imaging. JJ Totman, L Marciani, S Foley,E Campbell, CL Hoad, IA Macdonald, RC Spillerand PA Gowland. Physiol Meas. 2009 Oct;30(10):1117-36

Effects of meal composition and gender on postprandial small bowel water content. L Marciani, CL Hoad, EF Cox, JJ Totman, SE Pritchard, PA Gowland, RC Spiller. Gastroenterological 2009 May;136:5 A221

Mechanism of enhanced satiety after a soup compared to equicaloric mixed solid/liquid meal: delayed gastric emptying, enhanced gallbladder contraction and small bowel content. L Marciani, N Hall, SE Pritchard, JJ Totman, CL Hoad, PA Gowland, RC Spiller. Gastroenterological 2009 May;136:5 A328

Soup meal delays gastric emptying, enhances gallbladder contraction and increases small bowel water content and satiety compared to equicaloric mixed solid/liquid meal. L Marciani, N Hall, SE Pritchard, JJ Totman, CL Hoad, PA Gowland, RC Spiller. GUT, 2009. Apr;58:1 A30-A31

Evaluation of a robotic arm for echocardiography to X-ray image registration during cardiac catheterization procedures. Ma Y, Penney GP, Bos D, Frissen P, de Fockert G, King A, Gao G, Yao C, Totman J, Ginks M, Rinaldi C, Razavi R, Rhode KS.Conf Proc IEEE Eng Med Biol Soc. 2009;5829-32.

Performance evaluation and MR compatibility assessment of an optical fibre based pre-clinical MR-compatible PET scanner. JE Mackewn, D Strul, G Charles-Edwards, T Schaeffter,JJ Totman, WA Hallett, P Halsted, RA Page, D Cash, SF Keevil, SCR Williams, PK Marsden. Nuclear Science Symposium Conference Record, Orlando, Florida USA 2009.

A Fiducial Marker Based Technique for Alignment of Simultaneously Acquired PET and MRI Images. J. E. Mackewn, G. Charles-Edwards, JJ Totman, C Tsoumpas, P Halsted, EJ Somer, SF Keevil, and PK Marsden. IEEE Nuclear Science Symposium Medical Imaging Conference pp. 3307-3310, 2009

PET motion correction using simultaneous PET-MR acquisition and MR-derived motion fields. C Tsoumpas, J Mackewn, A King, C Buerger, JJ Totman, T Schaeffter and P Marsden. 2009 J Nucl Med 50 (Supplement 2), 532

Intra-abdominal adiposity and individual components of the metabolic syndrome in adolescence: Gender differences and underlying mechanisms. C Syme, M Abrahamowicz, GT Leonard, M Perron, A Pitiot, X Qiu, L Richer, JJ Totman, S Veillette, Y Xiao, D Gaudet, T Paus and Z Pausova. Arch Pediatr Adolesc Med. 2008;162(5):453-461.

Water proton T1 Measurements in brain tissue at 7 T, 3 T and 1.5 T using IR-EPI, IR-TSE and MPRAGE: results and optimization. PJ Wright, O Mougin, JJ Totman, A Peters, M Brookes, R coxon, P Morris, Clemence M, Francis S, Bowtell R and PA, Gowland 2008 MAGMA 21: 121-130

Non-invasive quantification of small bowel water content by MRI: a validation study. CL Hoad, L Marciani, S Foley, JJ Totman, J Wright, D Bush, EF Cox, E Campbell, RC Spiller and PA Gowland 2007 Phys. Med. Biol. 52 6909-6922

Abnormalities of small bowel and colonic water content in diarrhoea-predominant irritable bowel syndrome: Novel insights from magnetic resonance imaging. L Marciani, S Foley, CL Hoad, E Campbell, JJ Totman, E Cox, PA Gowland, and RC Spiller. Gut, 56:A65 (Suppl. 2), 2007.

Accelerated small bowel transit and contracted transverse colon in diarrhoea-predominant irritable bowel syndrome (IBS-D): novel insights from magnetic resonance imaging (MRI). L Marciani, S Foley, CL Hoad, E Campbell, JJ Totman, E Cox, PA Gowland and RC Spiller. Gastroenterology 132(S4); A141, 2007.

Parametric mapping of the Hepatic Perfusion Index with Gadolinium-enhanced Volumetric MRI. MJ White, RL O'Gorman, EM Charles-Edwards, PA Kane, JB Karani, MO Leach, and JJ Totman. BJR. 2007;80:113-120

Null Point Imaging: a Joint Acquisition/Analysis Paradigm for MR Classification. A Pitiot, JJ Totman and PA Gowland. Proc. 10th International Conference on Medical Image Computing and Computer Assisted Intervention. (MICCAI), Brisbane, Australia 759-66 2007

Bran-Induced Small Bowel Secretion: Assessment By Novel Non-Invasive Mri Technique. L Marciani, JJ Totman, CL Hoad, ST Evans, A Mistry, PA Gowland, RC Spiller. University of Nottingham Institute of Clinical Research Summer meeting 2006

Comparison of the Hepatic Perfusion Index Measured with Gadolinium-enhanced Volumetric MRI in Controls and in Patients with Colorectal Cancer. JJ Totman, RL O’Gorman, PA Kane and JB Karani. BJR. 2005;78:105-109

 

 

Patents Held
 NA

 

 

Scientific Awards
 NA

 

 

Funding Received
 NA