Name : Mary Stephenson
Title : Dr
Current Position :

Senior Research Fellow CIRC;

Adjunct Researcher, NUS Dept Medicine

Email address : mary.stephenson@nus.edu.sg
Contact Number : 66013525
Employment History

Senior Research Fellow : CIRC, Singapore (Aug 2013-present)

Research Fellow  : University of Nottingham. (Oct 2008 – Aug 2013)

 

 

Qualifications

The University of Nottingham, Nottingham, UK (2001 - 2009)

PhD Physics and Astronomy

Title: Multi-Nuclear Magnetic Resonance Spectroscopy of Human Energy Metabolismat High and Ultra-High field.

 

MSci (Hons) Physics (Class 2:1)

 

 

Research Interest
Throughout my PhD and Post-Doc at the University of Nottingham I specialised in investigating pathways for human metabolism using in vivo Magnetic Resonance Spectroscopy (MRS) and my main research interests lie in using multi-nuclear MRS, particularly 1H, 13C and 31P nuclei, in combination with other MRI techniques (ASL, fMRI, T2*mapping and DTI), to gain further insight into healthy human metabolism, as well as to understand how metabolism is perturbed in pathologies including diabetes, non-alcoholic fatty liver disease, myopathies, psychiatric and neurodegenerative diseases.

 

 

Publications

Blazejewska AI, Schwarz ST, Pitiot A, Stephenson MC, Lowe J Bajaj N, Bowtell RW, Auer DP, Gowland PA,  In vivo imaging of nigrosome loss in Parkinson's disease, Neurology (2013).

Hall EL, Stephenson MC, Price D, Morris PG, Methodology for Improved Detection of Low Concentration Metabolites in MRS: Optimised Coil Combination and Ultra-High Field. NeuroImage, (2013).

Johnston RD, Stephenson MC, Crossland H, Cordon SM, Taylor MA,  Aithal GP, Macdonald IA, The hepatic effects of a high fructose versus a high glucose diet in healthy overweight men, Gastroenterology (2013)


Stephenson MC, Leverton E, Khoo EYH, Poucher SM, Johansson L, Lockton JA, Eriksson JW, Mansell P, Morris PG, MacDonald IA, Variability in Fasting Lipid and Glycogen Content in Hepatic and Skeletal Muscle Tissue in Subjects with and without Type 2 Diabetes: A 1H and 13C MRS Study,NMR Biomed. (2013)


Lin Y, Stephenson MC, Xin L, Napolitano A, MorrisPG. Investigating the metabolic changes due to visual stimulation using functional proton magnetic resonance spectroscopy at 7T. J. Cereb. Blood Flow and Metab. (2012)


Khoo EYStephenson MCLeverton ECross REriksson JWPoucher SMSpendlove IMorris PGMacdonald IAMansell PAithal GPElevation of Alanine Transaminase and Markers of Liver Fibrosis After a Mixed Meal Challenge in Individuals with Type 2 Diabetes.Dig Dis Sci. (2012).


Stephenson MC, Gunner F, Simpson EJ, Greenhaff P, Francis ST, MacDonald IA, and Morris PG, Applications of Multi-Nuclear Magnetic Resonance Spectroscopy at 7T, World Journal of Radiology, 3(4), pp105-113 (2011).


Brookes MJ, Woolrich M, Luckhoo H, Hale J, Price D, Stephenson MC, Barnes GP, Smith SM, Morris, PG.Investigating the Electrophysiological Basis of Resting State Networks using Magnetoencephalography. PNAS, 108(40), pp16783-8, (2011)


Awad S, Stephenson M.C, Placidi E, Marciani L, Constantin-Teodosiu D, Gowland PA, Spiller RC, Fearon KCH, Morris PG, Macdonald IA, Lobo DN. The effects of fasting and refeeding with a ‘metabolic preconditioning’ drink on substrate reserves and mononuclear cell mitochondrial functionClinical Nutrition, (2010)


Stagg C.J, Best J.G, Stephenson M, O’Shea J, Wylezinska-Arridge M, Kincses Z.T, Morris P, Matthews P.M , Johansen-Berg H. Polarity sensitive modulation of cortical neural activity by transcranial direct current stimulation. J. Neuroscience (2009)


J.G. Best, C.J. Stagg, M. Stephenson, P.M. Matthews, P. Morris, H. Johansen-Berg, 7T magnetic resonance spectroscopy can be used safely and effectively to investigate the metabolic effects of transcranial direct current stimulation, Brain Stimulation, 1(3) pp263, (2008)


C.J. Stagg, J. Best, M. Stephenson, O'Shea J., Z.T. Kincses, U. Kischka, P. Morris, P.M. Matthews, H. Johansen-BergImaging the functional and neurochemical effects of transcranial direct current stimulation: a rationale for rehabilitation, Brain Stimulation, 1(3) pp260, (2008).

 

Book Contributions:

Francis ST, Sanchez-Panchuelo RM, Stephenson MC, Chapter 3: Neural Activation Imaging of book ‘Biomedical Imaging: Applications and Advances’, Woodhead Publishing (2014)

 

Patents Held
NA

 

Scientific Awards

ISMRM Summa Cum Laude Award (2012)


ISMRM Magna Cum Laude Award (2012)


University of Nottingham Staff Travel Prize (2012)

 

Funding Received

Project Title: CIRC/P/2014/006: Non-invasive assessment of metabolic adaptation in critical care survivors.  2014 – 2016  S$50,000

Role: Co-Investigator

 

Project Title: Application of Pulsed Electro Magnetic Fields (PEMFs) using a Clinical MRI scanner for improving Muscle Mass and Function in Patients with Lower Limb Fractures. 2014-2016  S$50,00.

Role: Co-Investigator

 

Project Title: CIRC/P/2014/005: A study using perfusion MRI and MR spectroscopy to evaluate anti-NR2A mediated cognitive dysfunction in SLE patients. S$35,000 2014-2016

Role: Collaborator.